Description
Coripren (Enalapril, Lercanidipine) Coated Tablets 10 mg/10 mg.
Coripren is a combination medication that contains two active ingredients: Enalapril and Lercanidipine. It is available in the form of coated tablets with each tablet containing 10 mg. of Enalapril and 10 mg. of Lercanidipine. Coripren is commonly prescribed for the treatment of hypertension (high blood pressure) and other cardiovascular conditions.
Enalapril
Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that works by blocking the conversion of angiotensin I to angiotensin II, a hormone that causes blood vessels to constrict. By inhibiting this process, Enalapril helps to relax and widen the blood vessels, which in turn lowers blood pressure and improves blood flow to the heart.
Lercanidipine
Lercanidipine is a calcium channel blocker that works by blocking the influx of calcium ions into the smooth muscle cells of the blood vessels. This action results in the relaxation of the blood vessels, leading to a decrease in blood pressure and improved blood flow. Lercanidipine is particularly effective in dilating the peripheral arteries and reducing the resistance to blood flow in the body.
Indications
Coripren is indicated for the treatment of hypertension (high blood pressure) in patients who require dual therapy with an ACE inhibitor and a calcium channel blocker. It may also be prescribed for the management of other cardiovascular conditions as determined by a healthcare provider.
Dosage and Administration
Coripren tablets are typically taken orally with a glass of water. The recommended dosage may vary depending on the individual patient’s condition and response to treatment. It is important to follow the instructions provided by the healthcare provider and not exceed the prescribed dose.
Contraindications
Coripren is contraindicated in patients with a known hypersensitivity to Enalapril, Lercanidipine, or any other ingredients in the formulation. It should not be used in patients with a history of angioedema related to previous ACE inhibitor therapy, severe aortic stenosis, or severe hepatic impairment.
Adverse Reactions
Common side effects of Coripren may include dizziness, headache, fatigue, cough, and peripheral edema. Serious adverse reactions such as hypotension, renal impairment, and angioedema may also occur. Patients should seek medical attention if they experience any unusual or severe side effects while taking Coripren.
Precautions
Patients taking Coripren should be monitored regularly for blood pressure and renal function. It is important to inform the healthcare provider of any existing medical conditions, allergies, or medications being taken to avoid potential interactions or adverse effects. Pregnant or breastfeeding women should consult a healthcare provider before using Coripren.
Storage
Coripren should be stored at room temperature away from moisture and heat. Keep the tablets in their original packaging and out of reach of children. Do not use Coripren beyond the expiration date printed on the packaging.
Conclusion
Coripren is a combination medication containing Enalapril and Lercanidipine, two active ingredients that work synergistically to lower blood pressure and improve cardiovascular health. It is commonly prescribed for the treatment of hypertension and other related conditions. Patients should adhere to the prescribed dosage and precautions to ensure the safe and effective use of Coripren.
