Description

Mefenamic Acid Coated Tablets 500 mg.

Mefenamic acid is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used to relieve pain, inflammation, and fever. It is available in the form of coated tablets, with each tablet containing 500mg of mefenamic acid. This medication is commonly prescribed to treat various conditions such as menstrual pain, headache, dental pain, musculoskeletal pain, and other forms of acute pain.

Indications

Mefenamic acid is indicated for the relief of mild to moderate pain associated with conditions such as:

• Menstrual pain (dysmenorrhea)
• Headache
• Dental pain
• Musculoskeletal pain
• Acute pain

Mechanism of Action

Mefenamic acid works by inhibiting the enzyme cyclooxygenase (COX), which is involved in the production of prostaglandins. Prostaglandins are chemicals in the body that are responsible for pain, inflammation, and fever. By inhibiting COX, mefenamic acid reduces the production of prostaglandins, thereby reducing pain and inflammation.

Dosage and Administration

The usual dose of mefenamic acid is 500mg to 1000mg per day, divided into two to four doses. The tablets should be taken with food to reduce the risk of gastrointestinal side effects. It is important to follow the dosage instructions provided by your healthcare provider and not exceed the recommended dose.

Contraindications

Mefenamic acid is contraindicated in individuals with a history of hypersensitivity to NSAIDs, asthma, urticaria, or other allergic reactions after taking aspirin or other NSAIDs. It should not be used in patients with active peptic ulcer disease, severe heart failure, or severe renal impairment.

Adverse Effects

Common side effects of mefenamic acid include gastrointestinal disturbances such as nausea, indigestion, and abdominal pain. Other side effects may include dizziness, headache, and rash. In rare cases, mefenamic acid may cause more serious side effects such as gastrointestinal bleeding, ulceration, or perforation.

Precautions

Patients taking mefenamic acid should be monitored for signs of gastrointestinal bleeding, ulceration, or perforation. It is important to use the lowest effective dose for the shortest duration possible to reduce the risk of side effects. Mefenamic acid should not be used in the third trimester of pregnancy as it may cause harm to the fetus.

Drug Interactions

Mefenamic acid may interact with other medications such as anticoagulants, antiplatelet drugs, corticosteroids, and selective serotonin reuptake inhibitors (SSRIs). These interactions may increase the risk of bleeding or other side effects. It is important to inform your healthcare provider about all the medications you are taking before starting mefenamic acid.

Storage

Store mefenamic acid tablets in a cool, dry place away from direct sunlight and moisture. Keep the tablets in their original packaging and out of reach of children. Do not use mefenamic acid after the expiration date printed on the packaging.

Conclusion

Mefenamic acid coated tablets 500mg are a commonly prescribed medication for the relief of pain and inflammation. It works by inhibiting the production of prostaglandins in the body, thereby reducing pain and inflammation. While effective, mefenamic acid should be used with caution and under the supervision of a healthcare provider to minimize the risk of side effects. If you experience any adverse effects while taking mefenamic acid, contact your healthcare provider immediately.