Description
Plestazol (cilostazol) Tablets 50 mg.
Description
Plestazol is a medication in the form of tablets containing 50 mg. of cilostazol. It is commonly prescribed to treat symptoms of intermittent claudication, a condition characterized by pain or cramping in the legs during physical activity due to reduced blood flow.
Indications
Plestazol is indicated for the improvement of walking distance in patients with intermittent claudication. It helps to reduce the symptoms of pain, cramping, and numbness in the legs that occur during physical activity.
Mechanism of Action
Cilostazol, the active ingredient in Plestazol, works by inhibiting an enzyme called phosphodiesterase III. This inhibition leads to vasodilation (widening of blood vessels) and inhibition of platelet aggregation, thereby improving blood flow to the extremities.
Dosage and Administration
The usual recommended dose of Plestazol is 100 mg. twice daily, taken at least half an hour before or two hours after a meal. The tablets should be swallowed whole with water and should not be crushed or chewed.
Contraindications
Plestazol is contraindicated in patients with a history of heart failure, bleeding disorders, or allergy to cilostazol. It should not be used in patients with severe liver or kidney impairment.
Side Effects
Common side effects of Plestazol may include headache, diarrhea, palpitations, and dizziness. In rare cases, more serious side effects such as bleeding, heart palpitations, or allergic reactions may occur.
Precautions
Patients taking Plestazol should be monitored for signs of bleeding, especially if they are also taking anticoagulants or antiplatelet medications. It is important to inform your healthcare provider about all medications you are currently taking before starting Plestazol.
Drug Interactions
Plestazol may interact with other medications, such as anticoagulants, antiplatelet agents, and certain antibiotics. It is important to consult with your healthcare provider before starting or stopping any medications while taking Plestazol.
Storage
Plestazol should be stored at room temperature away from moisture and heat. Keep the medication in its original packaging and out of reach of children.
Conclusion
Plestazol is a medication used to improve walking distance in patients with intermittent claudication. By increasing blood flow to the extremities, it helps reduce the symptoms of leg pain and cramping during physical activity. It is important to follow the prescribed dosage and instructions for taking Plestazol and to be aware of potential side effects and drug interactions. If you experience any concerning symptoms while taking Plestazol, contact your healthcare provider immediately.
