Description

Sodiofolin (Disodium Folate) Infusion

Sodiofolin, also known as disodium folinate, is a medication available in the form of infusions containing 100 mg. of the active ingredient in 50 mg/ml. concentration. Each vial contains 2 ml. of the infusion solution.

Overview

Sodiofolin is a prescription medication used for various medical conditions that require folate supplementation. It is commonly used in the treatment of certain types of anemia, as well as in combination with other medications for the management of certain cancers.

Composition

The active ingredient in Sodiofolin is disodium folinate, a form of folate that is easily absorbed by the body. Each vial contains 100 mg. of disodium folinate in a concentration of 50 mg/ml, with a total volume of 2 ml.

Indications

Sodiofolin is indicated for the following conditions:

• Treatment of megaloblastic anemia caused by folate deficiency
• Adjunctive treatment in certain types of cancer therapy, such as colorectal cancer
• Rescue therapy after high-dose methotrexate therapy

Dosage and Administration

The dosage of Sodiofolin may vary depending on the specific condition being treated and the individual patient’s response to the medication. It is typically administered by intravenous infusion under the supervision of a healthcare professional.

For megaloblastic anemia, the usual dose is 5-10 mg. of disodium folinate per day, administered for a period determined by the healthcare provider. In cancer therapy, the dosage and duration of treatment will be determined by the oncologist based on the specific protocol being followed.

Contraindications

Sodiofolin is contraindicated in patients with known hypersensitivity to folate or any of the components of the medication. It should not be used in patients with severe renal impairment or in those with a history of allergic reactions to similar medications.

Adverse Effects

Like all medications, Sodiofolin may cause side effects in some patients. Common side effects may include:

• Nausea and vomiting
• Diarrhea
• Stomach upset
• Allergic reactions

If any side effects are persistent or severe, patients should seek medical attention immediately. It is important to report any adverse reactions to the healthcare provider to ensure appropriate management.

Precautions

Before starting treatment with Sodiofolin, patients should inform their healthcare provider about any existing medical conditions, allergies, or medications they are currently taking. It is important to follow the prescribed dosage and administration instructions to ensure the safe and effective use of the medication.

Storage

Sodiofolin should be stored at room temperature, away from light and moisture. The vials should be kept in their original packaging until ready to use, and any unused portion should be discarded according to local regulations.

Conclusion

Sodiofolin is a valuable medication used in the treatment of various medical conditions that require folate supplementation. By following the prescribed dosage and administration guidelines, patients can benefit from the therapeutic effects of this medication while minimizing the risk of adverse effects.