Description
Actilize (Alteplase) 50 mg. Vial
Generic Name: Alteplase
Brand Name: Actilize
Strength: 50 mg.
Package Size: 1 vial
Description
Actilize is a medication that contains the active ingredient Alteplase. It is available in the form of a vial containing 50 mg. of Alteplase. Alteplase is a thrombolytic medication that is used to dissolve blood clots in various medical conditions.
Indications
Actilize is indicated for the treatment of acute ischemic stroke, acute myocardial infarction, and pulmonary embolism. It is also used in the management of acute peripheral arterial occlusion and acute deep vein thrombosis.
Mechanism of Action
Alteplase works by converting plasminogen into plasmin, which is an enzyme that breaks down fibrin clots in the blood vessels. This process helps to dissolve blood clots and restore blood flow to the affected areas, reducing the risk of complications associated with clot formation.
Dosage and Administration
The dosage of Actilize (Alteplase) depends on the medical condition being treated and the patient’s weight. It is usually administered intravenously by a healthcare professional in a hospital setting. The dose and duration of treatment will be determined by the healthcare provider based on the individual patient’s needs.
Side Effects
Common side effects of Actilize (Alteplase) may include bleeding, bruising, headache, nausea, vomiting, and fever. Serious side effects such as allergic reactions, severe bleeding, and stroke may occur in some patients. It is important to seek immediate medical attention if any serious side effects are experienced.
Contraindications
Actilize (Alteplase) is contraindicated in patients with a history of recent surgery, bleeding disorders, severe uncontrolled hypertension, or active internal bleeding. It should not be used in patients who have had a recent stroke, head trauma, or gastrointestinal bleeding.
Precautions
Before using Actilize (Alteplase), inform your healthcare provider about any medical conditions you have, especially if you are pregnant, breastfeeding, or have a history of bleeding disorders. It is important to follow the instructions of your healthcare provider carefully to minimize the risk of complications.
Drug Interactions
Alteplase may interact with other medications, such as anticoagulants, antiplatelet drugs, and nonsteroidal anti-inflammatory drugs (NSAIDs), increasing the risk of bleeding. It is important to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.
Storage
Store Actilize (Alteplase) vials at room temperature (20-25°C) away from light and moisture. Keep the vials out of reach of children and pets. Do not freeze the medication. Follow the storage instructions provided on the packaging.
Conclusion
Actilize (Alteplase) is a thrombolytic medication used to dissolve blood clots in various medical conditions. It is important to use this medication under the supervision of a healthcare professional to ensure its safe and effective use. If you experience any adverse reactions or have concerns about using Actilize, consult your healthcare provider for guidance.
