Description
Amicacina (Amikacin) Sulfate solution for injection 250 mg/ml. – 4 ml. Ampoules
Amicacina, also known as amikacin, is a potent antibiotic used to treat serious bacterial infections. It belongs to the aminoglycoside class of antibiotics and is commonly used when other antibiotics have failed or are not suitable for the infection being treated.
Composition:
The medicine is supplied in the form of a solution for injection, with each milliliter containing 250 mg. of amikacin sulfate. The solution is provided in 4 ml. ampoules, with each package containing 1 ampoule.
Indications:
Amicacina sulfate solution is indicated for the treatment of severe bacterial infections caused by susceptible organisms. It is commonly used to treat infections in the respiratory tract, urinary tract, skin and soft tissues, bones and joints, and septicemia.
Mechanism of Action:
Amicacina works by inhibiting protein synthesis in bacteria, leading to cell death. It binds to the bacterial ribosome, disrupting the production of essential proteins required for bacterial growth and replication.
Administration:
The solution for injection is administered intravenously or intramuscularly. The dosage and duration of treatment will vary depending on the type and severity of the infection, as well as the patient’s age, weight, and renal function.
Contraindications:
Amicacina sulfate solution should not be used in patients with a known hypersensitivity to aminoglycosides or any of the other ingredients in the formulation. It should be used with caution in patients with renal impairment or pre-existing hearing loss.
Adverse Effects:
Common side effects of amikacin include nephrotoxicity (kidney damage), ototoxicity (hearing loss), and neuromuscular blockade. Patients may also experience nausea, vomiting, and allergic reactions. Regular monitoring of renal function and hearing is recommended during treatment.
Precautions:
Prior to starting treatment with amicacina sulfate solution, it is important to perform a thorough assessment of the patient’s medical history, allergies, renal function, and hearing status. The medicine should be used with caution in pregnant or breastfeeding women, as well as in elderly patients.
Storage:
The ampoules should be stored at room temperature, away from light and moisture. Do not freeze the solution. Check the expiry date on the packaging and do not use the medicine if it has expired.
Conclusion:
Amicacina sulfate solution for injection is a valuable antibiotic used in the treatment of serious bacterial infections. It is important to follow the prescribed dosage and administration guidelines to ensure the optimal therapeutic outcome while minimizing the risk of adverse effects. Consult with a healthcare professional for further information and guidance on the use of this medication.