Description

Carbetocin 100 mcg/ml Injection

Carbetocin is a medication that is commonly used to prevent excessive bleeding after childbirth, particularly following cesarean sections or complicated deliveries. It belongs to a class of drugs known as uterotonic agents, which help to contract the uterus and control bleeding.

Composition:

Each vial of Carbetocin contains 100 micrograms of the active ingredient carbetocin in 1 milliliter (ml) of solution. Each pack contains 5 vials.

Indications:

Carbetocin is primarily used for the prevention of postpartum hemorrhage (excessive bleeding after childbirth) in women who are at risk due to various factors such as prolonged labor, multiple pregnancies, or previous history of bleeding disorders. It is particularly beneficial in cases where oxytocin (another uterotonic agent) is not effective or contraindicated.

Mechanism of Action:

Carbetocin works by mimicking the action of oxytocin, a hormone naturally produced by the body to stimulate uterine contractions during labor and delivery. By binding to oxytocin receptors in the uterus, carbetocin helps to enhance uterine muscle tone and reduce the risk of excessive bleeding.

Dosage and Administration:

The recommended dose of Carbetocin is usually administered as a single intravenous injection after the delivery of the baby and the placenta. The dosage may vary depending on the patient’s individual risk factors and the clinical situation. It is important to follow the healthcare provider’s instructions carefully when administering this medication.

Precautions:

• Carbetocin should be used with caution in patients with a history of cardiovascular disease, hypertension, or kidney problems.
• It is important to monitor vital signs and uterine contractions closely after administration to ensure the desired effect is achieved.
• Patients with known hypersensitivity to carbetocin or any of its components should not receive this medication.

Adverse Effects:

Common side effects of Carbetocin may include nausea, vomiting, headache, and dizziness. In some cases, it may also cause transient changes in blood pressure or heart rate. Serious adverse reactions such as allergic reactions or uterine rupture are rare but may occur in certain individuals.

Storage:

Carbetocin should be stored in a cool, dry place away from direct sunlight and heat. It should be kept out of reach of children and pets. Do not freeze the medication, and check the expiry date before use.

Conclusion:

Carbetocin is a valuable medication used in obstetrics to prevent postpartum hemorrhage and ensure the safety of both the mother and the newborn. By understanding its mechanism of action, dosage recommendations, precautions, and potential side effects, healthcare providers can effectively use Carbetocin to improve maternal outcomes during childbirth.