Description
Co-Diroton Tablets 10 mg/12.5 mg.
Co-Diroton tablets are a prescription medication that contains two active ingredients: perindopril erbumine (10 mg) and indapamide hemihydrate (12.5 mg). This combination medication is primarily used to treat hypertension (high blood pressure) in adults.
Composition:
The active ingredients in Co-Diroton tablets are:
- Perindopril erbumine – 10 mg.
- Indapamide hemihydrate – 12.5 mg.
Indications:
Co-Diroton tablets are indicated for the treatment of hypertension (high blood pressure) in adult patients. This medication is typically prescribed when blood pressure is not adequately controlled by monotherapy with either perindopril or indapamide alone.
Mechanism of Action:
Perindopril is an angiotensin-converting enzyme (ACE) inhibitor that works by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. Indapamide is a thiazide diuretic that helps reduce blood pressure by promoting diuresis (increased urine production) and vasodilation (widening of blood vessels).
Dosage and Administration:
Co-Diroton tablets should be taken orally with a full glass of water. The usual recommended dose is one tablet once daily, preferably in the morning before a meal. It is important to follow your doctor’s instructions regarding the dosage and duration of treatment.
Contraindications:
Co-Diroton tablets are contraindicated in patients who are hypersensitive to perindopril, indapamide, or any other component of the medication. This medication should not be used in patients with a history of angioedema related to previous ACE inhibitor therapy.
Side Effects:
Common side effects of Co-Diroton tablets may include dizziness, headache, fatigue, cough, and gastrointestinal disturbances. In rare cases, serious side effects such as angioedema, hypotension, electrolyte disturbances, and renal impairment may occur. If you experience any severe side effects, contact your healthcare provider immediately.
Warnings and Precautions:
Before taking Co-Diroton tablets, inform your doctor about any medical conditions you have, especially if you have kidney disease, liver disease, heart failure, or electrolyte imbalances. It is important to monitor your blood pressure regularly while taking this medication.
Drug Interactions:
Co-Diroton tablets may interact with other medications, including potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), lithium, and certain antidiabetic agents. Inform your healthcare provider about all the medications you are taking to avoid potential drug interactions.
Storage:
Store Co-Diroton tablets at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the tablets after the expiration date printed on the packaging.
Conclusion:
Co-Diroton tablets are a combination medication used to treat hypertension by lowering blood pressure through the synergistic action of perindopril and indapamide. It is essential to follow your doctor’s instructions carefully and report any side effects or concerns during the course of treatment. If you have any questions about Co-Diroton tablets, consult your healthcare provider for further information.
