Description
Coripren (enalapril, lercanidipine) Coated Tablets 10 mg/10 mg. #28
Coripren is a combination medication containing two active ingredients, enalapril and lercanidipine, in coated tablet form. Each tablet contains 10 mg. of enalapril and 10 mg. of lercanidipine, and this package contains 28 tablets.
Enalapril
Enalapril is an angiotensin-converting enzyme (ACE) inhibitor. It works by blocking the conversion of angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this enzyme, enalapril helps to relax blood vessels, reduce blood pressure, and improve blood flow to the heart.
Lercanidipine
Lercanidipine is a calcium channel blocker that works by blocking calcium channels in the blood vessels. This action helps to relax and widen the blood vessels, reducing the workload on the heart and lowering blood pressure.
Indications
Coripren is indicated for the treatment of hypertension (high blood pressure) in patients who require dual therapy with an ACE inhibitor and a calcium channel blocker.
Dosage and Administration
The recommended dosage of Coripren is one tablet (10 mg/10 mg) taken orally once daily. It is important to take the medication at the same time each day, with or without food, as directed by your healthcare provider.
Contraindications
- Hypersensitivity to enalapril, lercanidipine, or any other components of the medication
- History of angioedema related to previous ACE inhibitor therapy
- Severe renal impairment (creatinine clearance <30 mL/min)
- Pregnancy and breastfeeding
Side Effects
Common side effects of Coripren may include dizziness, headache, cough, swelling of the ankles, and flushing. If you experience any severe or persistent side effects, contact your healthcare provider immediately.
Drug Interactions
Coripren may interact with other medications, including potassium-sparing diuretics, potassium supplements, nonsteroidal anti-inflammatory drugs (NSAIDs), and lithium. Inform your healthcare provider about all medications you are currently taking to avoid potential interactions.
Precautions
- Monitor blood pressure regularly while taking Coripren
- Avoid alcohol consumption while on this medication
- Use caution when driving or operating machinery until you know how Coripren affects you
- Avoid sudden changes in body position to prevent dizziness
Storage
Store Coripren in a cool, dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets. Do not use Coripren after the expiration date printed on the packaging.
Conclusion
Coripren is a combination medication containing enalapril and lercanidipine, two active ingredients that work together to lower blood pressure in patients with hypertension. It is important to follow the dosage and administration instructions provided by your healthcare provider and to be aware of potential side effects and drug interactions. If you have any questions or concerns about Coripren, consult your healthcare provider for further guidance.
