Description

Coripren (enalapril, lercanidipine) Coated Tablets 20 mg/10 mg. #28

Coripren is a combination medication that contains two active ingredients: enalapril and lercanidipine. It is available in the form of coated tablets with a strength of 20 mg. of enalapril and 10 mg. of lercanidipine. Each pack contains 28 tablets.

Enalapril

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor that works by blocking the enzyme that converts angiotensin I to angiotensin II, a potent vasoconstrictor. By inhibiting this enzyme, enalapril helps relax and widen blood vessels, which in turn lowers blood pressure and improves blood flow to the heart.

Lercanidipine

Lercanidipine is a calcium channel blocker that works by blocking the influx of calcium into smooth muscle cells in the blood vessels. This action helps to relax and widen the blood vessels, leading to a reduction in blood pressure and an improvement in blood flow.

Indications

Coripren is indicated for the treatment of hypertension (high blood pressure) in patients who require combination therapy with an ACE inhibitor and a calcium channel blocker. It is used to help control blood pressure and reduce the risk of complications associated with hypertension, such as heart disease, stroke, and kidney problems.

Dosage and Administration

The recommended dose of Coripren is one tablet taken orally once daily, preferably in the morning. It can be taken with or without food. The tablets should be swallowed whole with a glass of water and should not be chewed or crushed.

It is important to follow the dosage instructions provided by your healthcare provider and not exceed the recommended dose unless directed to do so. Do not stop taking Coripren suddenly without consulting your doctor, as this can lead to a sudden increase in blood pressure.

Precautions

Before taking Coripren, inform your doctor if you have any allergies to enalapril, lercanidipine, or any other medications. Also, let your doctor know about any medical conditions you have, especially kidney disease, liver disease, heart disease, or electrolyte imbalances.

Coripren may cause dizziness or lightheadedness, especially during the first few days of treatment or when the dose is increased. Avoid driving or operating machinery until you know how this medication affects you. Limit alcoholic beverages while taking Coripren, as alcohol can further lower blood pressure and increase the risk of side effects.

Side Effects

Common side effects of Coripren may include dizziness, headache, fatigue, cough, and swelling of the hands or feet. These side effects are usually mild and temporary. However, if you experience any severe or persistent side effects, contact your doctor immediately.

Serious side effects of Coripren may include allergic reactions, chest pain, irregular heartbeat, difficulty breathing, or swelling of the face, lips, or throat. Seek immediate medical attention if you experience any of these symptoms.

Drug Interactions

Coripren may interact with other medications, including other blood pressure-lowering drugs, potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and certain antibiotics. Inform your doctor about all the medications you are taking, including prescription, over-the-counter, and herbal supplements.

It is important to avoid taking potassium supplements or potassium-containing salt substitutes while using Coripren, as this can increase the risk of hyperkalemia (high potassium levels in the blood).

Storage

Store Coripren tablets at room temperature away from moisture and heat. Keep the medication out of reach of children and pets. Do not use Coripren after the expiration date printed on the packaging.

Conclusion

Coripren is a combination medication that contains enalapril and lercanidipine, two drugs that work together to help lower blood pressure and improve blood flow. It is used in the treatment of hypertension and can be an effective option for patients who require combination therapy with an ACE inhibitor and a calcium channel blocker.

It is important to follow the dosage instructions provided by your healthcare provider and to be aware of the potential side effects and drug interactions associated with Coripren. If you have any questions or concerns about this medication, consult your doctor for further guidance.