Description

Cvetipin (Quetiapine) Coated Tablets 100 mg.

Cvetipin (quetiapine) coated tablets are a medication commonly prescribed to treat various mental health conditions, including schizophrenia, bipolar disorder, and major depressive disorder. Each tablet contains 100 mg. of quetiapine, an atypical antipsychotic drug that works by affecting the balance of neurotransmitters in the brain.

Indications

Cvetipin tablets are indicated for the treatment of schizophrenia in adults and adolescents aged 13-17 years. They are also used as monotherapy for the acute treatment of manic episodes associated with bipolar I disorder, both as monotherapy and as adjunctive therapy to lithium or divalproex. In addition, Cvetipin is prescribed for the treatment of depressive episodes associated with bipolar disorder, as well as for the maintenance treatment of bipolar I disorder.

Mechanism of Action

Quetiapine, the active ingredient in Cvetipin tablets, is classified as an atypical antipsychotic agent. It exerts its therapeutic effects through a combination of dopamine D2 and serotonin type 2 (5HT2) receptor antagonism. Quetiapine also has a high affinity for adrenergic alpha1 and histamine H1 receptors, which may contribute to its sedative and hypotensive effects.

Dosage and Administration

Cvetipin tablets are typically taken orally once daily with or without food. The dosage may vary depending on the condition being treated and the individual’s response to the medication. It is important to follow the dosage instructions provided by your healthcare provider and not to exceed the recommended dose.

For Schizophrenia:

• Adults: The recommended starting dose is 25 mg. twice daily, which can be increased gradually to a target dose of 300-450 mg. per day.
• Adolescents (13-17 years): The starting dose is 25 mg. twice daily, with a target dose of 400-800 mg. per day.

For Bipolar Disorder:

• Manic Episodes: The recommended starting dose is 50 mg. twice daily, which can be increased to a target dose of 400-800 mg. per day.
• Depressive Episodes: The starting dose is 50 mg. once daily, which can be increased to a target dose of 300 mg. per day.
• Maintenance Treatment: The recommended dose is 400-800 mg. per day.

Contraindications

Cvetipin tablets should not be used in patients with a known hypersensitivity to quetiapine or any other component of the product. They are also contraindicated in patients with a history of QT prolongation, recent myocardial infarction, uncontrolled hypertension, and severe hepatic impairment.

Adverse Reactions

Common adverse reactions associated with Cvetipin tablets include dizziness, somnolence, dry mouth, constipation, weight gain, and orthostatic hypotension. Less common but serious side effects may include neuroleptic malignant syndrome, tardive dyskinesia, and metabolic changes such as hyperglycemia and dyslipidemia.

Drug Interactions

Quetiapine, the active ingredient in Cvetipin tablets, may interact with other medications, leading to potential drug-drug interactions. It is important to inform your healthcare provider about all the medications you are currently taking, including prescription drugs, over-the-counter medicines, and herbal supplements.

Some common drug interactions with quetiapine include:

• Antidepressants
• Antifungal medications
• Anticonvulsants
• Antihypertensive drugs
• Antipsychotic medications
• CNS depressants

Precautions and Warnings

Before taking Cvetipin tablets, it is important to discuss your medical history with your healthcare provider, especially if you have a history of cardiovascular disease, diabetes, seizures, or liver problems. Quetiapine may cause drowsiness, so it is advisable to avoid driving or operating heavy machinery until you know how the medication affects you.

Quetiapine may also increase the risk of suicidal thoughts and behaviors, particularly in children, adolescents, and young adults. Close monitoring by a healthcare provider is essential during the initial phase of treatment and whenever the dosage is adjusted.

Storage

Cvetipin tablets should be stored at room temperature (20-25°C or 68-77°F) in a dry place away from moisture and heat. Keep the medication out of reach of children and pets and do not use it past the expiration date printed on the packaging.

Conclusion

Cvetipin (quetiapine) coated tablets are a valuable medication used in the treatment of various mental health conditions, including schizophrenia and bipolar disorder. By understanding the indications, mechanism of action, dosage, adverse reactions, drug interactions, precautions, and storage guidelines associated with Cvetipin tablets, patients can use this medication safely and effectively under the guidance of a healthcare provider.