Description

Enalozid (Enalapril, Hydrochlorothiazide) Tablets 25 mg. #30

Enalozid is a combination medication that contains two active ingredients, enalapril and hydrochlorothiazide, in a single tablet form. Enalapril belongs to a class of medications known as ACE inhibitors, while hydrochlorothiazide is a diuretic. This combination medication is commonly prescribed for the treatment of hypertension (high blood pressure) in adults.

Enalapril

Enalapril is an ACE inhibitor that works by blocking the action of angiotensin-converting enzyme (ACE), which is responsible for the production of angiotensin II. Angiotensin II is a substance in the body that causes blood vessels to constrict, leading to an increase in blood pressure. By inhibiting the action of ACE, enalapril helps to relax blood vessels and lower blood pressure.

Enalapril is also used in the treatment of heart failure and may improve symptoms such as shortness of breath and swelling in the legs due to fluid retention.

Hydrochlorothiazide

Hydrochlorothiazide is a diuretic, also known as a water pill, that works by increasing the amount of urine produced by the kidneys. This helps to reduce the amount of excess fluid in the body, which in turn lowers blood pressure. Hydrochlorothiazide is often used in combination with other medications to treat hypertension.

Additionally, hydrochlorothiazide may be prescribed for the treatment of edema (fluid retention) caused by conditions such as heart failure, liver disease, or kidney disorders.

Indications

Enalozid tablets are indicated for the treatment of hypertension in patients who require dual therapy with an ACE inhibitor and a diuretic. This combination medication is particularly useful for patients who do not achieve adequate blood pressure control with either enalapril or hydrochlorothiazide alone.

Enalozid may also be prescribed for the management of heart failure in patients who are stabilized on both enalapril and hydrochlorothiazide as individual medications.

Dosage and Administration

Enalozid tablets are available in a strength of 25 mg. of enalapril and 12.5 mg. of hydrochlorothiazide. The recommended dose of Enalozid is one tablet taken orally once daily, preferably in the morning. The tablets should be swallowed whole with a glass of water and can be taken with or without food.

It is important to follow the dosage instructions provided by your healthcare provider and not to exceed the recommended dose. If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

Contraindications

Enalozid tablets are contraindicated in patients with a history of hypersensitivity to enalapril, hydrochlorothiazide, or any other component of the medication. This medication should not be used in patients with a history of angioedema (swelling of the face, lips, throat, or tongue) related to previous ACE inhibitor therapy.

Enalozid is also contraindicated in patients with severe renal impairment (creatinine clearance <30 mL/min), anuria (absence of urine production), or a history of sulfonamide allergy.

Warnings and Precautions

Before starting Enalozid therapy, inform your healthcare provider about any medical conditions you have, especially kidney disease, liver disease, heart disease, diabetes, or gout. Your healthcare provider should also be aware of any allergies you have and any medications you are currently taking, including over-the-counter drugs, supplements, and herbal products.

It is important to monitor your blood pressure regularly while taking Enalozid tablets, as well as your kidney function and electrolyte levels. Report any signs of dehydration, such as excessive thirst, dry mouth, or decreased urination, to your healthcare provider immediately.

Enalozid may cause dizziness or lightheadedness, especially during the first few days of therapy or when the dose is increased. Avoid driving or operating machinery until you know how this medication affects you. Limit alcohol consumption, as it can further lower blood pressure and increase the risk of side effects.

Side Effects

Common side effects of Enalozid may include:

• Cough
• Dizziness
• Fatigue
• Headache
• Nausea
• Increased urination

These side effects are usually mild and may go away as your body adjusts to the medication. However, if any of these side effects persist or worsen, contact your healthcare provider.

Serious side effects of Enalozid that require immediate medical attention include:

• Chest pain
• Irregular heartbeat
• Swelling of the face, lips, throat, or tongue
• Sudden weight gain
• Fainting
• Signs of high potassium (muscle weakness, slow or irregular heartbeat)

If you experience any of these serious side effects, seek medical help right away.

Drug Interactions

Enalozid may interact with other medications or substances, potentially affecting how it works or increasing the risk of side effects. Inform your healthcare provider about all the medications you are taking, including prescription drugs, over-the-counter medicines, vitamins, and herbal supplements.

Some common drug interactions with Enalozid include:

• Nonsteroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen
• Potassium supplements or potassium-sparing diuretics
• Lithium
• Digoxin
• Certain antidiabetic medications

Your healthcare provider may need to adjust the dosages of your medications or monitor you more closely for side effects if you are taking Enalozid in combination with any of the above-listed drugs.

Storage

Store Enalozid tablets at room temperature away from moisture and heat. Keep the medication in its original packaging and out of reach of children and pets. Do not use Enalozid tablets beyond the expiration date printed on the packaging.

Conclusion

Enalozid tablets are a combination medication containing enalapril and hydrochlorothiazide, used for the treatment of hypertension and heart failure in adults. This medication works by relaxing blood vessels and reducing fluid retention, ultimately lowering blood pressure.

It is important to follow the dosage instructions provided by your healthcare provider, monitor your blood pressure regularly, and report any side effects or concerns to your healthcare provider. Enalozid may interact with other medications, so inform your healthcare provider about all the drugs you are taking.

By understanding how Enalozid works, its potential side effects, and how to use it safely, you can effectively manage your blood pressure and improve your overall health with the guidance of your healthcare provider.