Description

Filstim (Filgrastim) 1.6 ml. (48 ml. IU) 0.48 mg. #1 Syringe

Filstim is a medication that contains the active ingredient Filgrastim. It is available in a pre-filled syringe with a volume of 1.6 ml, which corresponds to 48 ml. International Units (IU) or 0.48 mg. Each syringe is labeled as number 1 and is designed for single use.

What is Filgrastim?

Filgrastim is a human granulocyte colony-stimulating factor (G-CSF) that is produced using recombinant DNA technology. It is a synthetic version of a naturally occurring protein in the body that stimulates the production of white blood cells in the bone marrow. White blood cells are essential for fighting off infections and maintaining a healthy immune system.

Indications

Filstim, containing Filgrastim, is commonly prescribed for the following indications:

• Treatment of neutropenia: Neutropenia is a condition characterized by a low level of neutrophils, a type of white blood cell. Filgrastim helps stimulate the production of neutrophils to prevent infections in patients undergoing chemotherapy or bone marrow transplantation.
• Prevention of febrile neutropenia: Febrile neutropenia is a serious complication in cancer patients undergoing chemotherapy. Filgrastim can help reduce the risk of developing febrile neutropenia by boosting white blood cell counts.
• Mobilization of peripheral blood progenitor cells: Filgrastim is also used to mobilize stem cells from the bone marrow into the bloodstream for collection and subsequent transplantation in patients undergoing certain cancer treatments.

How to Use Filstim

Before using Filstim, carefully read the instructions provided by your healthcare provider or pharmacist. The medication is typically administered as a subcutaneous injection, which means it is injected under the skin. Follow these general steps for using the Filstim syringe:

1. Wash your hands thoroughly with soap and water.
2. Clean the injection site with an alcohol swab and let it dry.
3. Remove the syringe from its packaging and check for any visible particles or discoloration in the solution. Do not use if the solution is cloudy or contains particles.
4. Hold the syringe with the needle pointing upwards and remove the needle cover.
5. Gently pinch the skin at the injection site and insert the needle at a 45-degree angle.
6. Push the plunger to inject the medication slowly and steadily.
7. Once the injection is complete, remove the needle and apply pressure to the site with a clean cotton ball or gauze.
8. Dispose of the used syringe in a sharps container as per local regulations.

It is important to rotate injection sites to prevent skin irritation or lipoatrophy (loss of fat tissue) at the injection sites. Your healthcare provider will determine the appropriate dosage and frequency of Filstim based on your specific medical condition and response to treatment.

Side Effects

Like all medications, Filstim can cause side effects in some patients. Common side effects may include:

• Injection site reactions such as redness, swelling, or pain
• Flu-like symptoms such as fever, chills, or muscle aches
• Headache
• Fatigue
• Nausea or vomiting

If any of these side effects persist or worsen, notify your healthcare provider promptly. In some cases, Filstim may cause more severe side effects, such as allergic reactions or respiratory problems. Seek immediate medical attention if you experience difficulty breathing, chest pain, or severe skin reactions.

Precautions

Before using Filstim, inform your healthcare provider if you have any allergies to Filgrastim or any other medications. Discuss your medical history, especially of blood disorders, lung disease, or kidney problems. It is important to disclose all the medications you are currently taking, including prescription drugs, over-the-counter medications, and herbal supplements.

During treatment with Filstim, avoid close contact with individuals who have contagious illnesses, as your immune system may be weakened. It is recommended to practice good hygiene, such as frequent hand washing, to reduce the risk of infections.

Storage

Store Filstim syringes in the original packaging at room temperature away from light and moisture. Do not freeze the medication. Keep out of reach of children and pets. Do not use expired Filstim or if the solution appears discolored or contains particles.

Conclusion

Filstim (Filgrastim) is a medication used to stimulate the production of white blood cells in patients with neutropenia or undergoing certain cancer treatments. It is administered as a subcutaneous injection using pre-filled syringes. While Filstim can be effective in preventing infections and managing febrile neutropenia, it may cause side effects in some individuals. It is essential to follow the instructions provided by your healthcare provider and report any adverse reactions promptly.