Description

Glibenclamide Tablets 5 mg.

Glibenclamide tablets are a type of medication used to treat type 2 diabetes. They contain the active ingredient glibenclamide, which belongs to a class of drugs called sulfonylureas. Glibenclamide works by helping the pancreas produce more insulin and by helping the body use insulin more effectively.

Indications

Glibenclamide tablets are indicated for the treatment of type 2 diabetes in adults. They are usually prescribed when diet and exercise alone have not been sufficient to control blood sugar levels.

Dosage and Administration

The usual starting dose of glibenclamide tablets is 2.5 mg. to 5 mg. once daily with breakfast or the first main meal. The dose may be adjusted based on the individual’s blood sugar levels and response to the medication. The maximum recommended dose is 15 mg. per day.

Contraindications

Glibenclamide tablets are contraindicated in patients with a history of hypersensitivity to sulfonylureas or any of the ingredients in the tablets. They should not be used in patients with type 1 diabetes, diabetic ketoacidosis, severe renal impairment, or severe hepatic impairment.

Adverse Effects

Common side effects of glibenclamide tablets include hypoglycemia (low blood sugar), weight gain, gastrointestinal symptoms such as nausea and diarrhea, and skin reactions such as rash and itching. Rare but serious side effects may include severe hypoglycemia, allergic reactions, and liver toxicity.

Drug Interactions

Glibenclamide tablets may interact with other medications, including certain antibiotics, antifungal agents, and beta-blockers. It is important to inform your healthcare provider of all medications you are taking, including over-the-counter drugs and herbal supplements, before starting glibenclamide.

Precautions

Patients taking glibenclamide tablets should regularly monitor their blood sugar levels as directed by their healthcare provider. They should also be aware of the signs and symptoms of hypoglycemia and know how to treat it. Alcohol consumption may increase the risk of hypoglycemia and should be limited while taking glibenclamide.

Storage

Glibenclamide tablets should be stored at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use glibenclamide tablets past the expiration date printed on the packaging.

Conclusion

Glibenclamide tablets are a commonly prescribed medication for the treatment of type 2 diabetes. They work by stimulating insulin production and improving the body’s response to insulin. While effective in controlling blood sugar levels, glibenclamide tablets can cause side effects and interactions with other medications. It is important to follow the dosage and administration instructions provided by your healthcare provider and to report any adverse effects promptly.