Description
Legalon sIL Powder for Solution for Infusion 350 mg.
Legalon sIL is a medication available in the form of a powder for solution for infusions. Each pack contains 4 vials, with each vial containing 350 mg. of the active ingredient. This medicine is commonly used in the treatment of various liver conditions and is known for its hepatoprotective properties.
Composition
The active ingredient in Legalon sIL is silybin, which is a flavonoid derived from the milk thistle plant. Silybin is known for its antioxidant and anti-inflammatory properties, making it effective in protecting the liver from damage caused by toxins, alcohol, and other harmful substances.
Indications
Legalon sIL is indicated for the treatment of various liver conditions, including:
- Acute and chronic hepatitis
- Fatty liver disease
- Drug-induced liver damage
- Cirrhosis
- Jaundice
Mechanism of Action
Silybin, the active ingredient in Legalon sIL, exerts its hepatoprotective effects through multiple mechanisms:
- Antioxidant activity – Silybin acts as a potent antioxidant, scavenging free radicals and reducing oxidative stress in the liver.
- Anti-inflammatory effects – Silybin helps reduce inflammation in the liver, thereby protecting hepatocytes from damage.
- Stimulation of liver regeneration – Silybin promotes the regeneration of liver cells, aiding in the repair of damaged tissue.
Dosage and Administration
Legalon sIL powder for Solution for Infusion should be administered by healthcare professionals through intravenous infusion. The recommended dosage for adults is:
- One vial (350 mg) daily for acute liver conditions
- One vial (350 mg) two to three times a week for chronic liver conditions
Contraindications
Legalon sIL should not be used in patients with known hypersensitivity to silybin or any other ingredients in the formulation. It is also contraindicated in pregnant and breastfeeding women.
Adverse Effects
Common side effects of Legalon sIL may include:
- GI disturbances such as nausea and vomiting
- Headache
- Allergic reactions
Severe adverse effects are rare but may include liver toxicity in patients with pre-existing liver conditions.
Precautions
Patients with liver disease should use Legalon sIL with caution and under the supervision of a healthcare professional. Regular monitoring of liver function tests is recommended during treatment. Avoid alcohol consumption while taking this medication.
Interactions
Legalon sIL may interact with certain medications, including:
- Anticoagulants – Silybin may increase the risk of bleeding when used with blood thinners
- Antihypertensives – Silybin may enhance the effects of blood pressure-lowering medications
Storage
Store Legalon sIL powder for Solution for Infusion in a cool, dry place away from direct sunlight. Keep out of reach of children. Do not use the medication past the expiration date printed on the packaging.
Conclusion
Legalon sIL powder for Solution for Infusion is a valuable medication for the treatment of liver conditions, offering hepatoprotective benefits through its active ingredient silybin. When used appropriately and under medical supervision, Legalon sIL can help improve liver function and promote liver health.
