Description
Maninil (glibenclamide) Tablets 5 mg.
Maninil tablets contain the active ingredient glibenclamide, which belongs to a class of medications called sulfonylureas. Glibenclamide is used to treat type 2 diabetes by helping the pancreas to produce more insulin and increasing the body’s sensitivity to insulin.
Indications
Maninil tablets are indicated for the treatment of type 2 diabetes in adults when diet and exercise alone are not enough to control blood sugar levels. It is used to improve glycemic control and lower the risk of complications associated with diabetes.
Dosage and Administration
The usual starting dose of Maninil tablets is 1.25-2.5 mg. once daily with breakfast or the first main meal of the day. The dose may be adjusted based on the individual’s blood sugar levels. The maximum recommended dose is 20 mg. per day.
Contraindications
Maninil tablets should not be used in patients with type 1 diabetes, diabetic ketoacidosis, severe kidney or liver impairment, or a history of hypersensitivity to sulfonylureas. It should not be used in pregnant or breastfeeding women.
Side Effects
Common side effects of Maninil tablets include hypoglycemia (low blood sugar), gastrointestinal upset, skin reactions, and weight gain. Rare but serious side effects may include liver toxicity and blood disorders. If any side effects are experienced, it is important to consult a healthcare provider.
Precautions
Patients taking Maninil tablets should monitor their blood sugar levels regularly and be aware of the signs of hypoglycemia. Alcohol consumption can increase the risk of hypoglycemia and should be limited. The medication may interact with other drugs, so it is important to inform the healthcare provider of all medications being taken.
Storage
Maninil tablets should be stored at room temperature (15-30°C) in a dry place away from direct sunlight and moisture. Keep the medication out of reach of children and pets.
Overdose
In case of overdose, symptoms may include hypoglycemia, confusion, seizures, and coma. Immediate medical attention should be sought if an overdose is suspected.
Warnings
Maninil tablets should not be used as the sole treatment for diabetes and should be taken in conjunction with diet and exercise. The medication may cause hypoglycemia, so caution should be exercised while driving or operating machinery.
Conclusion
Maninil tablets containing glibenclamide are an effective treatment for type 2 diabetes when used as directed by a healthcare provider. It is important to follow the prescribed dosage and monitor blood sugar levels regularly to achieve optimal glycemic control and reduce the risk of complications associated with diabetes.





