Description
Noliprel Bi-forte Coated Tablets 10/2.5 mg.
Noliprel Bi-forte coated tablets are a prescription medication used to treat high blood pressure (hypertension). Each tablet contains a combination of two active ingredients: perindopril erbumine and indapamide hemihydrate. This specific formulation contains 10 mg. of perindopril erbumine and 2.5 mg. of indapamide hemihydrate.
Indications
Noliprel Bi-forte is indicated for the treatment of essential hypertension in adults. It is often prescribed when treatment with a single antihypertensive agent is not sufficient to control blood pressure.
Mechanism of Action
Perindopril erbumine is an angiotensin-converting enzyme (ACE) inhibitor that works by blocking the conversion of angiotensin I to angiotensin II. This helps to relax blood vessels and reduce blood pressure. Indapamide hemihydrate is a thiazide-like diuretic that helps the body eliminate excess salt and water, further lowering blood pressure.
Dosage and Administration
Noliprel Bi-forte tablets are typically taken once daily, preferably in the morning before a meal. The usual starting dose is one tablet (10/2.5 mg) per day, but your doctor may adjust the dose based on your individual response. It is important to follow your doctor’s instructions carefully and not exceed the recommended dosage.
Contraindications
Noliprel Bi-forte should not be used in patients with a history of angioedema related to previous ACE inhibitor therapy, severe kidney impairment, or hypersensitivity to any of the ingredients in the product. It is also contraindicated during pregnancy and breastfeeding.
Adverse Effects
Common side effects of Noliprel Bi-forte may include dizziness, headache, fatigue, dry cough, and low blood pressure. In rare cases, more serious side effects such as angioedema, hyperkalemia, and renal impairment may occur. If you experience any unusual symptoms while taking this medication, contact your healthcare provider immediately.
Drug Interactions
It is important to inform your doctor about all medications, supplements, and herbal products you are taking before starting Noliprel Bi-forte. This medication may interact with other antihypertensive agents, potassium-sparing diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and lithium, among others.
Storage
Store Noliprel Bi-forte tablets in their original packaging at room temperature, away from moisture and heat. Keep this medication out of reach of children and pets. Do not use expired tablets and dispose of them properly according to local regulations.
Conclusion
Noliprel Bi-forte coated tablets are a combination medication used to treat hypertension by lowering blood pressure through different mechanisms of action. It is important to take this medication as prescribed by your doctor and to report any side effects or concerns promptly. By following your healthcare provider’s guidance and maintaining regular follow-up appointments, you can effectively manage your hypertension and improve your overall health.
