Description
Propofol-Novo Suspension for Infusion – 10 mg/ml, 20 ml, N5
Introduction:
Propofol-Novo is a medication used for sedation and anesthesia during medical procedures. It is a sterile, white, oil-in-water emulsion that is administered intravenously. Each milliliter of Propofol-Novo suspension contains 10 mg. of propofol. This medication comes in a 20 ml. vial and is available in a pack of 5 vials.
Indications:
Propofol-Novo is indicated for general anesthesia, monitored anesthesia care, and sedation for intubation and mechanical ventilation in the intensive care unit. It is also used for procedural sedation in various medical settings.
Mechanism of Action:
Propofol acts as a gamma-aminobutyric acid (GABA) agonist, enhancing the inhibitory effects of GABA in the central nervous system. This results in sedation, hypnosis, and anesthesia.
Administration:
Propofol-Novo is administered intravenously by healthcare professionals trained in anesthesia and sedation. The dose is titrated based on the patient’s weight, age, and medical condition to achieve the desired level of sedation or anesthesia.
Contraindications:
- Hypersensitivity to propofol or any of the components in the formulation
- Severe respiratory depression
- Severe hypotension
- Severe hepatic impairment
Adverse Effects:
Common side effects of Propofol-Novo include hypotension, respiratory depression, pain at the injection site, and bradycardia. Rare but serious side effects may include propofol infusion syndrome, which can lead to metabolic acidosis, rhabdomyolysis, and cardiac failure.
Warnings and Precautions:
- Respiratory monitoring is essential during and after administration of propofol.
- Patients should be closely monitored for signs of propofol infusion syndrome.
- Propofol should be used with caution in patients with cardiovascular disease or compromised respiratory function.
Storage:
Propofol-Novo should be stored at room temperature away from light and moisture. Do not freeze the medication. Once opened, use the vial immediately and discard any unused portion.
Conclusion:
Propofol-Novo is a valuable medication used for sedation and anesthesia in a variety of medical settings. Healthcare providers should be aware of its indications, contraindications, and potential adverse effects in order to safely administer the medication to patients. Proper monitoring and dose titration are essential to ensure the best outcomes for patients receiving Propofol-Novo.
