Description
Streptocinaza (Streptokinase) Lyophilizate for Solution for Infusion 1,500,000 IU #1 Vial
Streptocinaza, also known as streptokinase, is a medication available in lyophilized form for solution for infusion. Each vial contains 1,500,000 International Units (IU) of streptocinaza. This medication is primarily used for its thrombolytic properties, meaning it helps to dissolve blood clots in the body. It is commonly used in the treatment of conditions such as myocardial infarction (heart attack), pulmonary embolism, and ischemic stroke.
How Streptocinaza Works
Streptocinaza works by activating the conversion of plasminogen to plasmin, which is an enzyme that breaks down fibrin, the protein that forms blood clots. By promoting the formation of plasmin, streptocinaza helps to break down blood clots that may be causing blockages in blood vessels. This mechanism of action is crucial in the treatment of conditions where the formation of blood clots can be life-threatening.
Indications
Streptocinaza is indicated for use in the following conditions:
- Acute myocardial infarction (heart attack)
- Pulmonary embolism
- Ischemic stroke
- Acute arterial thrombosis
- Deep vein thrombosis
Administration
Streptocinaza is administered via intravenous infusion. The lyophilized powder in the vial must be reconstituted with a compatible diluent according to the manufacturer’s instructions. The reconstituted solution should be visually inspected for particulate matter or discoloration before administration. The infusion rate and dosage of streptocinaza will vary depending on the indication being treated and the patient’s condition. It is important to follow the prescribed dosing regimen as directed by a healthcare professional.
Adverse Effects
Like all medications, streptocinaza may cause side effects in some individuals. Common adverse effects of streptocinaza may include:
- Bleeding or hemorrhage
- Allergic reactions
- Low blood pressure
- Fever
- Chills
It is important to report any adverse effects experienced during streptocinaza treatment to a healthcare provider for further evaluation and management.
Contraindications
Streptocinaza should not be used in individuals with the following conditions:
- Active internal bleeding
- Recent major surgery or trauma
- History of stroke or intracranial hemorrhage
- Severe uncontrolled hypertension
- Pregnancy
It is essential to discuss any pre-existing medical conditions or medications with a healthcare provider before starting streptocinaza treatment to ensure its safety and efficacy.
Storage
The streptocinaza lyophilizate vial should be stored according to the manufacturer’s instructions. It is typically recommended to store the vial at room temperature away from light and moisture. Once reconstituted, the solution should be used immediately or as directed by a healthcare professional.
Conclusion
Streptocinaza, in the form of lyophilizate for solution for infusion, is a potent thrombolytic medication used in the treatment of various conditions associated with blood clots. By promoting the breakdown of fibrin and dissolving blood clots, streptocinaza plays a crucial role in restoring blood flow and preventing life-threatening complications. It is important to use streptocinaza under the guidance of a healthcare professional and to be aware of its potential adverse effects and contraindications. With proper administration and monitoring, streptocinaza can be a valuable tool in the management of thrombotic disorders.