Description
Ultibro Brizchailer
Ultibro Brizchailer is a medication that comes in the form of capsules containing a combination of glycopyrronium and indacaterol. Each capsule contains 110 mcg of glycopyrronium and 50 mcg of indacaterol. This medication is commonly prescribed to help manage respiratory conditions such as chronic obstructive pulmonary disease (COPD).
Indications
Ultibro Brizchailer is indicated for the long-term maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also used to reduce exacerbations and improve symptoms such as shortness of breath, coughing, and wheezing associated with COPD.
Mechanism of Action
Glycopyrronium is a long-acting muscarinic antagonist that works by blocking the action of acetylcholine at muscarinic receptors in the airways, leading to bronchodilation. Indacaterol is a long-acting beta2-adrenergic agonist that stimulates beta2-adrenergic receptors in the airways, resulting in bronchodilation and relaxation of the smooth muscles in the lungs.
Dosage and Administration
Ultibro Brizchailer capsules are for oral inhalation only. The usual dose is one capsule once daily, at the same time each day. The capsules should be used with the inhaler device provided. It is important to follow the instructions provided with the medication for proper use of the inhaler.
Contraindications
Ultibro Brizchailer is contraindicated in patients with a known hypersensitivity to glycopyrronium, indacaterol, or any of the other ingredients in the medication. It should not be used in patients with a history of hypersensitivity reactions to anticholinergic or sympathomimetic drugs.
Side Effects
Common side effects of Ultibro Brizchailer may include dry mouth, constipation, urinary retention, blurred vision, cough, and throat irritation. Serious side effects such as worsening of COPD symptoms, chest pain, palpitations, and allergic reactions may occur in some patients.
Precautions
Ultibro Brizchailer should be used with caution in patients with a history of cardiovascular disease, diabetes, thyroid disorders, or urinary retention. It is important to monitor for signs of worsening respiratory symptoms and to seek medical attention if symptoms do not improve or worsen.
Drug Interactions
Ultibro Brizchailer may interact with other medications, such as anticholinergic drugs, beta-blockers, and monoamine oxidase inhibitors (MAOIs). It is important to inform your healthcare provider about all the medications you are currently taking before starting Ultibro Brizchailer.
Storage
Ultibro Brizchailer capsules should be stored at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep the capsules in their original packaging and out of reach of children and pets.
Conclusion
Ultibro Brizchailer is a combination medication containing glycopyrronium and indacaterol that is used for the management of COPD. It works by relaxing the muscles in the airways, leading to improved breathing and reduced symptoms of COPD. It is important to follow the prescribed dosage and administration instructions and to be aware of the potential side effects and precautions associated with this medication.