Description
Apsibin (Capecitabine) Coated Tablets 150 mg.
Apsibin is a medication available in the form of coated tablets containing 150 mg. of the active ingredient Capecitabine. It is commonly prescribed by healthcare professionals for the treatment of certain types of cancer, particularly breast cancer and colorectal cancer. Capecitabine is classified as an antimetabolite and belongs to a class of medications known as fluoropyrimidines.
Indications
Apsibin (Capecitabine) is indicated for the treatment of the following conditions:
- Metastatic breast cancer
- Adjuvant (post-surgery) treatment of colon cancer
- Metastatic colorectal cancer
Mechanism of Action
Capecitabine is a prodrug, meaning it is converted into its active form (5-FU) in the body. 5-FU is a cytotoxic agent that works by interfering with the synthesis of DNA and RNA in cancer cells, ultimately leading to cell death. Capecitabine is preferentially activated in cancer cells, which helps target the treatment to the affected tissues while minimizing damage to healthy cells.
Dosage and Administration
Apsibin (Capecitabine) Tablets are typically taken orally with water, usually within 30 minutes after a meal. The dosage and treatment duration may vary depending on the individual’s condition and response to treatment. It is important to follow the dosage instructions provided by your healthcare provider and not exceed the prescribed amount.
Side Effects
As with any medication, Apsibin (Capecitabine) may cause side effects in some individuals. Common side effects may include:
- Nausea and vomiting
- Diarrhea
- Hand-foot syndrome (palmar-plantar erythrodysesthesia)
- Fatigue
- Loss of appetite
If you experience severe or persistent side effects, it is important to notify your healthcare provider immediately. They may adjust your dosage or recommend additional supportive care to manage these side effects.
Precautions
Before starting treatment with Apsibin (Capecitabine), inform your healthcare provider about any existing medical conditions, allergies, or medications you are currently taking. Caution should be exercised in patients with impaired liver or kidney function, as dosage adjustment may be necessary.
It is important to use effective contraception during treatment with Capecitabine, as it may cause harm to an unborn baby. Pregnant or breastfeeding women should not use this medication without consulting their healthcare provider.
Drug Interactions
Capecitabine may interact with other medications, including but not limited to:
- Warfarin
- Phenytoin
- Leucovorin
- Sorivudine
Inform your healthcare provider about all the medications you are currently taking to avoid potential drug interactions and complications.
Storage
Store Apsibin (Capecitabine) Tablets at room temperature, away from moisture and heat. Keep the medication out of reach of children and pets. Do not use the tablets if they are past the expiration date or show signs of deterioration.
Conclusion
Apsibin (Capecitabine) coated tablets are an important medication used in the treatment of various types of cancer. By understanding the indications, mechanism of action, dosage and administration, side effects, precautions, and drug interactions associated with this medication, patients can make informed decisions about their treatment plan in collaboration with their healthcare providers.
