Description

Cefotaxim (Cefotaxime) Powder 1g – #1 Vial

Cefotaxim, also known as cefotaxime, is a broad-spectrum antibiotic used to treat a variety of bacterial infections. It belongs to the cephalosporin class of antibiotics and is commonly prescribed for infections that are resistant to other antibiotics.

Overview

Cefotaxim is a sterile, white to pale yellow powder that is usually reconstituted with a diluent to form a solution for intravenous or intramuscular administration. It is available in vials containing 1 gram of cefotaxime powder.

Indications

Cefotaxim is indicated for the treatment of various bacterial infections, including:

• Respiratory tract infections
• Skin and soft tissue infections
• Urinary tract infections
• Joint and bone infections
• Intra-abdominal infections
• Sepsis

Mechanism of Action

Cefotaxim works by interfering with the synthesis of the bacterial cell wall, leading to cell death. It is effective against a wide range of bacteria, including both gram-positive and gram-negative organisms.

Dosage and Administration

The dosage of cefotaxim will vary depending on the type and severity of the infection being treated. It is typically administered by intravenous infusion or intramuscular injection. The reconstituted solution should be used within a specified time frame and at the recommended temperature.

Contraindications

Cefotaxim is contraindicated in patients with a known hypersensitivity to cephalosporin antibiotics or any of the components of the formulation. It should also be used with caution in patients with a history of allergic reactions to penicillin or other beta-lactam antibiotics.

Adverse Reactions

Common side effects of cefotaxim may include:

• Nausea and vomiting
• Diarrhea
• Rash
• Headache

Serious side effects, although rare, may include allergic reactions, severe skin reactions, and gastrointestinal disturbances. Patients should seek medical attention if they experience any severe or persistent side effects.

Precautions

Patients should be monitored for signs of an allergic reaction during treatment with cefotaxim. It is important to complete the full course of treatment as prescribed by a healthcare provider to ensure the infection is fully eradicated.

Drug Interactions

Cefotaxim may interact with other medications, including probenecid, aminoglycosides, and loop diuretics. Patients should inform their healthcare provider of all medications they are taking before starting treatment with cefotaxim.

Storage

Cefotaxim vials should be stored at room temperature away from moisture and light. Once reconstituted, the solution should be used promptly or discarded according to the manufacturer’s instructions.

Conclusion

In conclusion, cefotaxim is a valuable antibiotic used to treat a wide range of bacterial infections. It is important to follow the dosage and administration instructions provided by a healthcare provider and to be aware of potential side effects and drug interactions. If you have any questions or concerns about cefotaxim, consult with your healthcare provider for more information.